BIOTECH DATABASES FOR RESEARCHERS
BIOTECH DATABASES FOR RESEARCHERS
Genetic Databases
Protein and cell processes databases
BLAST
Align gene sequences and find homologues for your gene or probe sequence.
Entrez Gene
Open access searchable database for gene information based on multiple parameters such as gene name, PubMed publication, chromosome location, etc.
Entrez Nucleotide
The Entrez Nucleotide database is a collection of sequences from several sources, including GenBank, RefSeq, and PDB. The number of bases in these databases continues to grow at an exponential rate. As of April 2006, there are over 130 billion bases in GenBank and RefSeq alone.
Entrez SNP
Searchable database for SNPs from several different species.
Gene Ontology
The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products in different databases. The GO collaborators are developing three structured, controlled vocabularies (ontologies) that describe gene products in terms of their associated biological processes, cellular components and molecular functions in a species-independent manner.
Genecards
GeneCards is an integrated database of human genes that includes automatically-mined genomic, proteomic and transcriptomic information, as well as orthologies, disease relationships, SNPs, gene expression, gene function, and service links for ordering assays and antibodies.
HomoloGene
HomoloGene is a system for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes.
OMIM
A catalog of human genes and genetic disorders. The database contains textual information and references as well as copious links to MEDLINE, sequence records in the Entrez system as well as to other related resources.
ORF Finder
The ORF Finder (Open Reading Frame Finder) is a graphical analysis tool which finds all open reading frames of a selectable minimum size in a user's sequence or in a sequence already in the database. This tool identifies all open reading frames using the standard or alternative genetic codes.
Protein and cell process databases:
The Antibody Resource Page
A guide and links to a wide range of companies that sell antibodies and antibody-related products. Also has links to research, news and other information.
Conserved Domain Database
The Conserved Domain Database (CDD) contains protein domain models imported from outside sources, such as Pfam and SMART, and curated at NCBI. CDD contains over 12,000 such models and is linked to other NCBI databases, including protein sequences, bibliographic citations, and taxonomy.
KEGG pathway database
A collection of pathway maps representing our knowledge of molecular interactions and reaction networks for various cellular, metabolic, genetic and disease processes.
Post-translational modification predictions: Find candidate post-translational modification sites on a protein sequence.
O-glycosylation
N-glycosylation
Myristoylation
Phosphorylation
Sulfation
Sumoylation
Reactome
Reactome is a knowledgebase of core biochemical and signaling pathways and reactions in human cells and of the orthologous events in 22 other species.
Swiss-2DPAGE
Contains data on proteins identified on various 2-D PAGE and SDS-PAGE reference maps.
Tissue Expression
TissueInfo is a program that determines the tissue expression profile of a sequence. It does this by comparing the given sequence against the EST database. Each EST comes from a library derived from a specific tissue type. By collating the library information from the ESTs which a sequence matches, we can identify the tissue expression profile of that sequence.
UniProtKB/Swiss-Prot
A protein sequence database, which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases
Embryome
Embryomics™ represents the merger of new technologies in the field of genomics with the biology of embryonic stem cells to provide scientists with a detailed "roadmap" of the human developmental tree, the factors to push the cells into desired lineages, and tools to purify the desired cell types."
